Cannabinoid Research in Horses
41 studies
41 peer-reviewed studies examining CBD and other cannabinoids in horses, newest first, each linked to its source on PubMed. A reference index for information and education — evidence quality varies and this is not medical advice.
Cannabidiol-induced cellular and matrix-associated responses in primary equine sarcoid cells
Semik-Gurgul E, Ocłoń E, Zubel-Łojek J et al. · J Vet Intern Med · Year 2026 · Topic: Dermatology/Skin
View on PubMed →Overview of the Current Osteoarthritis Treatment in Veterinary Medicine and Future Directions
Quintão NLM, Moffa EB, Kroier M et al. · ACS Pharmacol Transl Sci · Year 2026 · Topic: Pain/Arthritis
View on PubMed →Metabolic effects and pharmacokinetics of oral cannabidiol (CBD) in Connemara ponies following 21 days of treatment
Wermer K, Berkecz R, Ilisz I et al. · Front Vet Sci · Year 2026 · Topic: Metabolic/Diabetes
View on PubMed →Differences in Plasma Exposure of Cannabidiol and Cannabidiolic Acid Following Oral Administration to Horses
Ekstrand C, Michanek P, Hernlund E et al. · J Vet Pharmacol Ther · Year 2026 · Topic: GI/IBD
View on PubMed →Short-Term Daily Oral Administration of Cannabidiol Does Not Impact Rebound Tonometry Intraocular Pressure or Schirmer Tear Test Values in Healthy Adult Horses
Diehl K, Sheridan C, Reed R. · Vet Ophthalmol · Year 2026
View on PubMed →Cannabidiol-rich extract suppresses the activation of proinflammatory genes IL-1β and IL-6 in equine mesenchymal stem cells stimulated with lipopolysaccharide
da Costa Kamura B, de Oliveira Ferreira LV, Chimenes ND et al. · Vet Res Commun · Year 2026 · Topic: Neuro/Cognitive
View on PubMed →Cannabinoid Receptors in the Horse Lateral Nucleus of the Amygdala: A Potential Target for Ameliorating Pain Perception, Stress and Anxiety in Horses
Bombardi C, Salamanca G, Tagliavia C et al. · Int J Mol Sci · Year 2025 · Topic: Anxiety/Stress
View on PubMed →Metabolism, pharmacokinetics, and bioavailability of cannabigerol in horses following intravenous and oral administration with micellar and oil formulations
Serrano-Rodríguez JM, Miraz R, Saitua A et al. · Front Vet Sci · Year 2025 · Topic: Pharmacokinetics
View on PubMed →Cannabinoid and cannabinoid related receptors in fibroblasts, inflammatory and endothelial cells of the equine hoof with and without laminitis: novel pharmacological target
Zamith Cunha R, Gobbo F, Morini M et al. · Front Vet Sci · Year 2025 · Topic: Pain/Arthritis
View on PubMed →Pharmacokinetics of cannabidiol and its two main phase I metabolites in Connemara ponies
Wermer K, Korbacska-Kutasi O, Berkecz R et al. · Front Vet Sci · Year 2025 · Topic: Pharmacokinetics
View on PubMed →Pharmacokinetics of a single oral administration of two cannabidiol formulations in fed and fasted horses
Di Salvo A, Bazzano M, Rocca GD et al. · Front Vet Sci · Year 2025 · Topic: Pain/Arthritis
View on PubMed →A Literature Review on Equine Bedding: Impacts on Horse and Human Welfare, Health, and the Environment
Masebo NT, Benedetti B, Mountricha M et al. · Animals (Basel) · Year 2025 · Topic: Review
View on PubMed →Effect of time of day and physical exercise on inflammatory biomarkers in athletic horses
Aragona F, Giannetto C, Piccione G et al. · Front Vet Sci · Year 2025 · Topic: Cancer
View on PubMed →Circadian Oscillation of Leukocyte Subpopulations and Inflammatory Cytokines over a 24-H Period in Horses
Aragona F, Rizzo M, Giudice E et al. · Vet Sci · Year 2025 · Topic: Cancer
View on PubMed →Dynamic Adaptation of Hematological Parameters, Albumin, and Non-Esterified Fatty Acids in Saddlebred and Standardbred Horses During Exercise
Piccione G, Arfuso F, Giudice E et al. · Animals (Basel) · Year 2025
View on PubMed →Incorporating a Behavioral Medicine Approach in the Multi-Modal Management of Chronic Equine Gastric Ulcer Syndrome (EGUS): A Clinical Commentary
Klinck M, Lovett A, Sykes B. · Animals (Basel) · Year 2025 · Topic: Pain/Arthritis
View on PubMed →In Vitro Immunomodulatory Effects of Equine Adipose Tissue-Derived Mesenchymal Stem Cells Primed with a Cannabidiol-Rich Extract
Battistin L, Moya LFA, Ferreira LVO et al. · Int J Mol Sci · Year 2025 · Topic: Cancer
View on PubMed →Effect of orally administered cannabidiol oil on daily tonometric curve in healthy Italian Saddle horses
Bazzano M, Laus F, Cerquetella M et al. · PLoS One · Year 2025
View on PubMed →The Best Protocol to Treat Equine Skin Wounds by Second Intention Healing: A Scoping Review of the Literature
Ribeiro G, Carvalho L, Borges J et al. · Animals (Basel) · Year 2024 · Topic: Dermatology/Skin
View on PubMed →Endocannabinoid system and phytocannabinoids in the main species of veterinary interest: a comparative review
Di Salvo A, Chiaradia E, Sforna M et al. · Vet Res Commun · Year 2024 · Topic: Pharmacokinetics
View on PubMed →Behavioral observations, heart rate and cortisol monitoring in horses following multiple oral administrations of a cannabidiol containing paste (part 2/2)
Eichler F, Ehrle A, Machnik M et al. · Front Vet Sci · Year 2024 · Topic: Anxiety/Stress
View on PubMed →Pharmacokinetics and tolerability of single-dose enteral cannabidiol and cannabidiolic acid rich hemp in horses (Equus caballus)
Thomson ACS, McCarrel TM, Zakharov A et al. · Front Vet Sci · Year 2024 · Topic: GI/IBD
View on PubMed →Cannabinoids in Integumentary Wound Care: A Systematic Review of Emerging Preclinical and Clinical Evidence
Niyangoda D, Muayad M, Tesfaye W et al. · Pharmaceutics · Year 2024 · Topic: Dermatology/Skin
View on PubMed →Improved quality of life and pain relief in mature horses with osteoarthritis after oral transmucosal cannabidiol oil administration as part of an analgesic regimen
Interlandi C, Tabbì M, Di Pietro S et al. · Front Vet Sci · Year 2024 · Topic: Anxiety/Stress
View on PubMed →Role of cannabidiolic acid or the combination of cannabigerol/cannabidiol in pain modulation and welfare improvement in horses with chronic osteoarthritis
Aragona F, Tabbì M, Gugliandolo E et al. · Front Vet Sci · Year 2024 · Topic: Pain/Arthritis
View on PubMed →Behavioral observations, heart rate and heart rate variability in horses following oral administration of a cannabidiol containing paste in three escalating doses (part 1/2)
Eichler F, Ehrle A, Jensen KC et al. · Front Vet Sci · Year 2023 · Topic: Anxiety/Stress
View on PubMed →Expression of cannabinoid (CB1 and CB2) and cannabinoid-related receptors (TRPV1, GPR55, and PPARα) in the synovial membrane of the horse metacarpophalangeal joint
Zamith Cunha R, Zannoni A, Salamanca G et al. · Front Vet Sci · Year 2023 · Topic: Pain/Arthritis
View on PubMed →Evaluation of an Oral Supplemental Cannabidiol Product for Acceptability and Performance in Mature Horses
Leise JM, Leatherwood JL, Paris BL et al. · Animals (Basel) · Year 2023 · Topic: Safety/Toxicology
View on PubMed →Pharmacokinetic modelling of orally administered cannabidiol and implications for medication control in horses
Eichler F, Poźniak B, Machnik M et al. · Front Vet Sci · Year 2023 · Topic: Anxiety/Stress
View on PubMed →Gabapentin: Clinical Use and Pharmacokinetics in Dogs, Cats, and Horses
Di Cesare F, Negro V, Ravasio G et al. · Animals (Basel) · Year 2023 · Topic: Seizures/Epilepsy
View on PubMed →The Clinical Pharmacology and Therapeutic Evaluation of Non-Steroidal Anti-Inflammatory Drugs in Adult Horses
Mercer MA, Davis JL, McKenzie HC. · Animals (Basel) · Year 2023 · Topic: Pain/Arthritis
View on PubMed →Expression of Cannabinoid Receptors in the Trigeminal Ganglion of the Horse
Zamith Cunha R, Semprini A, Salamanca G et al. · Int J Mol Sci · Year 2023 · Topic: Inflammation
View on PubMed →An update on animal models of intervertebral disc degeneration and low back pain: Exploring the potential of artificial intelligence to improve research analysis and development of prospective therapeutics
Alini M, Diwan AD, Erwin WM et al. · JOR Spine · Year 2023 · Topic: Pain/Arthritis
View on PubMed →The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse
Cunha RZ, Felisardo LL, Salamanca G et al. · Vet Anim Sci · Year 2023 · Topic: Seizures/Epilepsy
View on PubMed →Cannabidiol and the possibilities of its use in veterinary medicine of dogs and horses: A brief review
Landa L, Trojan V, Demlova R et al. · Vet Med (Praha) · Year 2022 · Topic: Seizures/Epilepsy
View on PubMed →The cannabinoid receptors system in horses: Tissue distribution and cellular identification in skin
Kupczyk P, Rykala M, Serek P et al. · J Vet Intern Med · Year 2022 · Topic: Dermatology/Skin
View on PubMed →Marijuana toxicosis in 2 donkeys
Fitzgerald AH, Magnin G, Pace E et al. · J Vet Diagn Invest · Year 2022 · Topic: Psychiatric
View on PubMed →Towards Non-Targeted Screening of Lipid Biomarkers for Improved Equine Anti-Doping
Tou K, Cawley A, Bowen C et al. · Molecules · Year 2022 · Topic: Inflammation
View on PubMed →Cannabis and Driving
Pearlson GD, Stevens MC, D'Souza DC. · Front Psychiatry · Year 2021 · Topic: Review
View on PubMed →Cellular distribution of cannabinoid-related receptors TRPV1, PPAR-gamma, GPR55 and GPR3 in the equine cervical dorsal root ganglia
Galiazzo G, De Silva M, Giancola F et al. · Equine Vet J · Year 2021 · Topic: Pain/Arthritis
View on PubMed →Ethnoveterinary practices of Covasna County, Transylvania, Romania
Bartha SG, Quave CL, Balogh L et al. · J Ethnobiol Ethnomed · Year 2015 · Topic: Dermatology/Skin
View on PubMed →
For information and education only. Always consult a veterinarian before using any supplement. We link to each source and do not reproduce copyrighted full text.